Uterine leiomyosarcoma with central nervous system metastases

نویسندگان

  • Carina Meira Abrahão
  • Fernando Cotait Maluf
چکیده

Leiomyosarcoma (LMS) is a rare tumour and comprises 2-3% of all malignant uterus neoplasms [1]. Leiomyosarcoma is characterised by aggressive behaviour, high recurrence rates, and poor overall survival, despite multimodal treatment [3]. Surgery is the main treatment and consists of total abdominal hysterectomy. A randomised trial consisting of 224 patients diagnosed with uterine sarcomas stage I and II showed that adjuvant radiotherapy improves locoregional control. The role of adjuvant chemotherapy is still unclear [1]. Unfortunately, roughly 50% of patients with organ-confined disease will usually develop distant metastasis to lung, peritoneum, liver, pelvic, and para-aortic lymph nodes. Brain metastases are extremely rare [5].

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عنوان ژورنال:

دوره 9  شماره 

صفحات  -

تاریخ انتشار 2015